United States securities and exchange commission logo March 19, 2021 Nello Mainolfi Founder, President and Chief Executive Officer Kymera Therapeutics, Inc. 200 Arsenal Yards Blvd., Suite 230 Watertown, Massachusetts 02472 Re: Kymera Therapeutics, Inc. Draft Registration Statement on Form S-1 Submitted March 17, 2021 CIK No. 0001815442 Dear Dr. Mainolfi: This is to advise you that we do not intend to review your registration statement. We request that you publicly file your registration statement no later than 48 hours prior to the requested effective date and time. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Irene Paik at 202-551-6553 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Nicole Daley - Goodwin Procter LLP